Author

G. P. Brownrigg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

E. J. Rideout· 3 shared J. W. Millington· 3 shared P. J. Basner-Collins· 3 shared Z. Sun· 3 shared C. Chao· 2 shared J. D. Johnson· 2 shared L. W. Wat· 2 shared B. Hudry· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

E. J. Rideout

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

β-Hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets.

R. Banerjee, Y. Zhu, G. P. Brownrigg, R. Moravcova, J. C. Rogalski, L. Foster, J. D. Johnson, J. Kolic

This study shows that β-hydroxybutyrate (βHB) increases insulin secretion and decreases glucagon secretion in human and mouse islets at physiological glucose concentrations.

bioRxiv · Feb 27, 2024Cell Biology

Sex differences in islet stress responses support female beta cell resilience

G. P. Brownrigg, Y. H. Xia, C. M. Jamie Chu, S. Wang, C. Chao, J. A. Zhang, S. Skovso, E. Panzhinskiy, X. Hu, J. D. Johnson, E. J. Rideout

This study identifies sex differences in beta cell stress responses, showing female beta cells are more resilient to ER stress in both human and mouse models.

bioRxiv · May 10, 2022 · PreprintCell Biology

A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

J. W. Millington, L. W. Wat, Z. Sun, P. J. Basner-Collins, G. P. Brownrigg, E. J. Rideout

This study shows that a low sugar diet increases body size in both male and female Drosophila larvae, but affects their insulin/TOR signaling and metabolism differently.

bioRxiv · Mar 3, 2021 · PreprintPhysiology

Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size

J. W. Millington, G. P. Brownrigg, P. J. Basner-Collins, Z. Sun, E. Rideout

This study shows that altering insulin/insulin-like growth factor signaling (IIS) activity in Drosophila larvae has sex-biased effects on body size, with inhibition reducing female size more than males and augmentation increasing male size more than females.

bioRxiv · Sep 4, 2020Physiology

Female-specific upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

J. W. Millington, C. Chao, Z. Sun, P. J. Basner-Collins, G. P. Brownrigg, L. W. Wat, B. Hudry, I. Miguel-Aliaga, E. J. Rideout

The paper identifies a female-specific increase in insulin pathway activity as the mechanism behind sex differences in nutrient-dependent body size plasticity in Drosophila.

bioRxiv · Apr 22, 2020Physiology