Author

J. W. Papatzimas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Medina· 1 shared D. Dieters-Castator· 1 shared D. Dovala· 1 shared D. J. Derksen· 1 shared D. K. Nomura· 1 shared E. S. Toriki· 1 shared G. Lajoie· 1 shared G. M. Siegers· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Medina

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2 papers

Recent·Most cited

BiochemistrybioRxivNov 4, 2022

Rational Chemical Design of Molecular Glue Degraders

E. S. Toriki, J. W. Papatzimas, K. Nishikawa…·D. K. Nomura

This paper develops a strategy to convert protein-targeting ligands into molecular glue degraders by identifying a covalent handle that induces proteasome-mediated degradation of target proteins.

DOI 10.1021/acscentsci.2c01317

experimental assaydrug response / drug discovery

ImmunologybioRxivJul 17, 2020

ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy

I. Dutta, D. Dieters-Castator, J. W. Papatzimas…·G. M. Siegers

This study identifies ADAM protease inhibition as a strategy to overcome resistance of breast cancer stem-like cells to γδ T cell immunotherapy by blocking MICA shedding.

DOI 10.1016/j.canlet.2020.10.013

humanproteomics