Author

D. Dieters-Castator

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

G. M. Siegers· 2 shared I. Dutta· 2 shared J. Schueler· 2 shared A. Brumwell· 1 shared A. Koromilas· 1 shared A. Medina· 1 shared B.-J. Guan· 1 shared C. Patsis· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

G. M. Siegers

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Author profile →

2 papers

Recent·Most cited

ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy

I. Dutta, D. Dieters-Castator, J. W. Papatzimas, A. Medina, J. Schueler, D. J. Derksen, G. Lajoie, L. M. Postovit, G. M. Siegers

This study identifies ADAM protease inhibition as a strategy to overcome resistance of breast cancer stem-like cells to γδ T cell immunotherapy by blocking MICA shedding.

bioRxiv · Jul 17, 2020Immunology

Translational control of breast cancer plasticity

M. Jewer, L. Lee, G. Zhang, J. Liu, S. D. Findlay, K. M. Vincent, K. Tandoc, D. Dieters-Castator, D. F. Quail, I. Dutta, M. Coatham, Z. Xu, B.-J. Guan, M. Hatzoglou, A. Brumwell, , L.-M. Postovit

The paper identifies hypoxia and drug-induced translational activation of NANOG, SNAIL, and NODAL isoforms that drive breast cancer plasticity and stem-cell-like phenotypes, with potential therapeutic implications.

bioRxiv · Apr 2, 2019Cancer Biology