Author

J. W. Tobias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

F. B. Johnson· 2 shared K. N. Estep· 2 shared R. J. Fernandez· 2 shared A. Babu· 1 shared A. Dhingra· 1 shared B. M. Beveridge· 1 shared C. J. Lengner· 1 shared D. B. Frank· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

F. B. Johnson

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Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 14, 2023

Transcriptomic changes predict metabolic alterations in LC3 associated phagocytosis in aged mice

A. Dhingra, J. W. Tobias, N. J. Philp, K. Boesze-Battaglia

The paper identifies transcriptomic changes in retinal pigment epithelial cells of aged mice lacking LC3b, linking them to metabolic dysregulation and inflammation.

DOI 10.1101/2023.03.14.532586

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintJan 19, 2023

Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere length maintenance

K. N. Estep, J. W. Tobias, R. J. Fernandez…·F. B. Johnson

This study investigates how human iPSCs respond to telomeric DNA breaks, showing ATR-mediated cell cycle arrest and telomerase-independent telomere maintenance via ALT.

DOI 10.1101/2023.01.19.524780

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivOct 28, 2020

GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

R. J. Fernandez, Z. J. G. Gardner, K. J. Slovik…·F. B. Johnson

This study shows that GSK3 inhibition improves growth and telomere function in DC patient-derived AT2 cells by enhancing Wnt signaling.

DOI 10.7554/elife.64430

humanbulk RNA-seq

𝕏 PostBluesky