Author

R. J. Fernandez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1

Frequent Co-Authors

F. B. Johnson· 3 shared C. J. Lengner· 2 shared J. W. Tobias· 2 shared K. N. Estep· 2 shared Q. Chen· 2 shared S. Root· 2 shared A. Babu· 1 shared B. M. Beveridge· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

F. B. Johnson

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Author profile →

4 papers

Recent·Most cited

Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere length maintenance

K. N. Estep, J. W. Tobias, R. J. Fernandez, B. M. Beveridge, F. B. Johnson

This study investigates how human iPSCs respond to telomeric DNA breaks, showing ATR-mediated cell cycle arrest and telomerase-independent telomere maintenance via ALT.

bioRxiv · Jan 19, 2023 · PreprintCell Biology

Edge-focused network-based approach: an improved kernel density estimator for home range

J. Vyasanakere, J. R. Mukherjee, R. J. Fernandez

This paper introduces EFNKDE, a network-based kernel density estimator for home range estimation that produces continuous and differentiable density estimates, outperforming existing methods in specific scenarios.

bioRxiv · Aug 21, 2022 · PreprintEcology

Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies

Y. Choi, M. S. Kim, J. H. Rhoades, N. M. Johnson, C. T. Berry, S. Root, Q. Chen, Y. Tian, R. J. Fernandez, Z. Cramer, S. Adams-Tzivelekidis, N. Li, F. B. Johnson, C. J. Lengner

The paper uses patient-derived iPS cells to model liver pathologies in telomeropathies and identifies AKT suppression as a potential therapeutic target.

bioRxiv · Nov 19, 2021Cell Biology

GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells

R. J. Fernandez, Z. J. G. Gardner, K. J. Slovik, D. C. Liberti, K. N. Estep, W. Yang, Q. Chen, G. T. Santini, J. V. Perez, S. Root, R. Bhatia, J. W. Tobias, A. Babu, M. P. Morley, D. B. Frank, , F. B. Johnson

This study shows that GSK3 inhibition improves growth and telomere function in DC patient-derived AT2 cells by enhancing Wnt signaling.

bioRxiv · Oct 28, 2020Cell Biology