K. Boesze-Battaglia

This study shows that Aa Cdt toxin disrupts macrophage phagocytic function by altering phosphoinositide pools and Rab5 association, leading to reduced bactericidal capacity and increased bacterial survival.

The paper identifies transcriptomic changes in retinal pigment epithelial cells of aged mice lacking LC3b, linking them to metabolic dysregulation and inflammation.

This study investigates how LtxA from Aggregatibacter actinomycetemcomitans enters and traffics within human lymphocytes, revealing its reliance on dynamin-dependent, clathrin-independent pathways and Rab5-mediated endocytic trafficking.

The paper investigates peroxisome activity and turnover in RPE cells, finding that catalase activity peaks in the morning and is regulated by LC3B, which affects autophagic organelle turnover.