Structure-Functional-Selectivity Relationship Studies on A-86929 Analogs and Small biaryl Fragments toward Discovery of biased D1 agonists
H. Li, R. Mirabel, J. Zimmerman, I. Ghiviriga, D. K. Phidd, N. M. Horenstein, N. M. Urs
This paper identifies chemical motifs for β-arrestin-biased D1R agonists through SAR studies of A-86929 analogs and small biaryl fragments.
bioRxiv · Oct 1, 2021 · PreprintPharmacology & Toxicology