Author

A. Koren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. D. Auerbach· 1 shared A. Dallmann· 1 shared A. Goldfarb· 1 shared A. L. H. Webster· 1 shared A. N. Bracci· 1 shared A. Rosenberg· 1 shared A.-M. Gonzalez· 1 shared B. Chang· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. D. Auerbach

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Author profile →

3 papers

Recent·Most cited

The evolution of the human DNA replication timing program

A. N. Bracci, A. Dallmann, Q. Ding, M. J. Hubisz, M. Caballero, A. Koren

This study examines replication timing evolution across humans, chimpanzees, and rhesus macaques, finding sequence-driven changes that impact gene regulation and chromatin structure.

bioRxiv · Aug 9, 2022Evolutionary Biology

Fanconi Anemia Pathway Deficiency Drives Copy Number Variation in Squamous Cell Carcinomas

A. L. H. Webster, M. A. Sanders, K. Patel, R. Dietrich, R. J. Noonan, F. P. Lach, R. R. White, A. Goldfarb, K. Hadi, M. M. Edwards, F. X. Donovan, M. Jung, S. Sridhar, O. Fedrigo, H. Tian, , P. Campbell

This paper shows that FA pathway deficiency in squamous cell carcinomas leads to high structural variant rates and copy number alterations, linking genomic instability to tumor progression.

bioRxiv · Aug 14, 2021 · PreprintCancer Biology

Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture

J. C. Rivera-Mulia, T. Sasaki, C. Trevilla-Garcia, N. Nakamichi, D. J. H. F. Knapp, C. Hammond, B. Chang, J. W. Tyner, M. Devidas, J. Zimmerman, K. Klein, V. Somasundaram, B. Druker, T. Gruber, A. Koren, , D. M. Gilbert

The paper compares DNA replication timing profiles of BCP-ALL leukemic samples with normal B-lineage differentiation stages to identify clinically relevant features.

bioRxiv · Apr 11, 2019 · PreprintCancer Biology