Author

J.-H. Cheong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

J. Kim· 2 shared J. Y. Lim· 2 shared A. Andersson-Rolf· 1 shared A.-M. Ada· 1 shared B.-K. Koo· 1 shared C. H. Kim· 1 shared D. E. Stange· 1 shared H. Kim· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

J. Kim

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeted Degradation of METTL3 Against Acute Myeloid Leukemia and Gastric Cancer.

K. Hwang, J. Bae, Y.-L. Jhe, J. Kim, J.-H. Cheong, T. Sim

This study develops KH12, a METTL3 degrader, showing potent anti-leukemia and anti-gastric cancer effects through m6A-dependent and -independent mechanisms.

bioRxiv · Feb 2, 2024Biochemistry

Acquired epithelial WNT secretion drives niche independence of developing gastric cancer

I. Teriyapirom, J. Kim, H. Lee, S. R. Merker, A. Andersson-Rolf, S. R. Jahn, A.-M. Ada, S.-M. Kim, J. Y. Lim, T. Schmaeche, N. Wetterling, S. Stegert, J.-Y. Park, J.-H. Cheong, H. Kim, , B.-K. Koo

The paper identifies WNT2B and WNT7B as key ligands maintaining gastric epithelium homeostasis and shows that gastric cancer gains WNT independence through epithelial secretion of WNT7B via MAPK activation.

bioRxiv · Feb 24, 2023 · PreprintCancer Biology

Serum albumin maintains Wnt water-solubility and activity

J. H. Yeo, S. S. Kwon, J. Chae, I. Kusen, J. Han, J. Y. Lim, J.-H. Cheong, T. I. Kim, Y. O. Jung, C. H. Kim, J. Lee

This study identifies serum albumin as a factor that maintains Wnt3a solubility and activity, enabling the development of serum-free Wnt3a preparations for therapeutic use.

bioRxiv · Jan 22, 2023 · PreprintBiochemistry