Author

Jacob A. Boyer

Ludwig Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Joshua D. RabinowitziD· 2 shared Abigail XieiD· 1 shared Alexander W. LoftusiD· 1 shared Ali Vaziri GohariD· 1 shared Andrew L. KungiD· 1 shared Angela M. MonteroiD· 1 shared Anusha MudigondaiD· 1 shared Armaan H. SiddiqueeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Joshua D. RabinowitzORCID

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2 papers

Recent·Most cited

A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism

Omid Hajihassani, Asael Roichman, Jacob A. Boyer, Michal MacArthur, Ricardo A. Cordova, Alexander W. Loftus, Christina S. Boutros, Jonathan J. Hue, Parnian Naji, Soubhi Tahhan, Peter Gallagher, William C. Beegan, Danyal Shah, James Choi, Nimat Manzoor, , Jordan Michael Winter

This study shows that a ketogenic diet enhances the effectiveness of glutamine metabolism inhibitors in pancreatic cancer by increasing tumor reliance on glutamine for energy.

Cell Reports Medicine · Apr 23, 2026Peer-reviewedCancer Biology

PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma

Katrina I. Paras, Julia S. Brunner, Jacob A. Boyer, Angela M. Montero, Benjamin T. Jackson, Sangita Chakraborty, Abigail Xie, Kristina C. Guillan, Armaan H. Siddiquee, Lourdes Pajuelo Torres, Joshua D. Rabinowitz, Andrew L. Kung, Daoqi You, Filemon S. Dela Cruz, Lydia W.S. Finley

This study shows that PAX3-FOXO1 drives metabolic vulnerabilities in rhabdomyosarcoma, making these cells sensitive to methotrexate.

Cancer Research · Sep 5, 2025Peer-reviewedCancer Biology