Author

Ali Vaziri Gohar

Loyola University Medical CenterORCID 0000-0002-6924-8691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam KneeboneiD· 1 shared Alexander W. LoftusiD· 1 shared Anusha MudigondaiD· 1 shared Arabela A. GrigorescuiD· 1 shared Asael RoichmaniD· 1 shared Ata AbbasiD· 1 shared Bakhtiar YaminiiD· 1 shared Christina S. BoutrosiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

Adam KneeboneORCID

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Author profile →

3 papers

Recent·Most cited

Cancer BiologyCell Reports MedicinePeer-reviewedApr 23, 2026

A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism

Omid Hajihassani, Asael Roichman, Jacob A. Boyer…·Jordan Michael Winter

This study shows that a ketogenic diet enhances the effectiveness of glutamine metabolism inhibitors in pancreatic cancer by increasing tumor reliance on glutamine for energy.

8 citationstop 1%

mousebulk RNA-seq

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedFeb 13, 2025

Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)

Paige J. Monsen, Prashant V. Bommi, Arabela A. Grigorescu…·Gary E. Schiltz

This study optimizes a PROTAC to degrade IDO1 with high potency in GBM cells, showing sustained degradation via the ubiquitin-proteasome system.

27 citationstop 1%

humanexperimental assay

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Cancer BiologybioRxivPreprintJan 15, 2025

Cytosolic transport of citrate protects nutrient-austere pancreatic cancer from ferroptosis

Adam Kneebone, Kailey Lindaur, Ata Abbas…·Ali Vaziri Gohar

This study identifies SLC25A1-mediated citrate transport as a mechanism protecting pancreatic cancer cells from ferroptosis under nutrient stress, with therapeutic implications for PDAC.

DOI 10.1101/2025.01.15.633097

humanproteomics

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