Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity
Ana Catarina Ferreira, Brittany M. Hemmer, Sarah M. Philippi, Alejandro Borja Grau-Perales, Jacob L. Rosenstadt, Hanxiao Liu, Jeffrey D. Zhu, Tatyana Kareva, Tim Ahfeldt, Merina Varghese, Patrick R. Hof, Joseph M. Castellano
This study shows that neuronal TIMP2 regulates hippocampus-dependent memory by controlling extracellular matrix accumulation and adult neurogenesis.
Molecular Psychiatry · Sep 1, 2023Peer-reviewedNeuroscience