Durable suppression of viremia by lipid nanoparticle-formulated RNA encoding for a highly potent HIV-1 neutralizing antibody
Sophie Sayettat, Felix Tolksdorf, Robin Johannson, Johannes Nelke, Alexandra Malz, Leyla Fischer, Imke Gerhard, Nathalie Ullrich, Ursula Ellinghaus, Christiane Stadler, Jan P. Bogen, Candice Morin, Jacqueline Knüfer, Ricarda Stumpf, Philipp Schommers, , Henning Gruell
This study demonstrates that lipid nanoparticle-formulated RNA encoding a potent HIV-1 neutralizing antibody can durably suppress viremia in humanized mice.
bioRxiv · Sep 19, 2026 · PreprintImmunology