Author

Jacqueline Lewis

Agency for Science, Technology and Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Prakash ArumugamiD· 3 shared Corinna Jie Hui Goh· 2 shared Jin Huei Wong· 2 shared Mohammad AlfatahiD· 2 shared Arshia NaaziD· 1 shared Kiat Whye KongiD· 1 shared Liang CuiiD· 1 shared Nimo AbdullahiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Prakash ArumugamORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genome-Wide CRISPR/Cas9 Screening Reveals Lipid Metabolism and Inflammatory Signalling as Modulators of Ganoderic Acid DM Cytotoxicity

Nimo Abdullah, Jacqueline Lewis, Prakash Arumugam

This study uses CRISPR/Cas9 screening to identify lipid metabolism and inflammatory signaling genes that modulate GA-DM cytotoxicity in melanoma cells.

Journal of Genetics · Jul 4, 2026Peer-reviewedGenomics

Metabolism of glucose activates TORC1 through multiple mechanisms in Saccharomyces cerevisiae

Mohammad Alfatah, Liang Cui, Corinna Jie Hui Goh, Trishia Yi Ning Cheng, Yizhong Zhang, Arshia Naaz, Jin Huei Wong, Jacqueline Lewis, Wei Jie Poh, Prakash Arumugam

This study identifies three distinct pathways by which glucose metabolism activates TORC1 in yeast, including both Rag GTPase-dependent and independent mechanisms.

Cell Reports · Oct 1, 2023Peer-reviewedGenetics

TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae

Mohammad Alfatah, Jin Huei Wong, Vidhya Gomathi Krishnan, Yong Cheow Lee, Quan Feng Sin, Corinna Jie Hui Goh, Kiat Whye Kong, Wei Ting Lee, Jacqueline Lewis, Shawn S. Hoon, Prakash Arumugam

This study shows TORC1 activates in response to glucose and regulates gene expression via the Tap42-Sit4-Rrd1/Rrd2 pathway, controlling yeast growth and development.

BMC Biology · May 6, 2021Peer-reviewedGenetics