Molecular BiologybioRxivPreprint
MethylHDA: One-pot helicase-dependent amplification with concurrent DNMT1-mediated maintenance of DNA methylation
Kiat Whye Kong, Si En Poh, Fong Tian Wong…·Winston Lian Chye Koh
The paper introduces MethylHDA, a method that combines helicase-dependent amplification with DNMT1 to preserve DNA methylation during targeted amplification.
DOI 10.64898/2026.03.05.709983