NERINE reveals rare variant associations in gene networks across phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson's disease
Sumaiya Nazeen, Xinyuan Wang, Autumn Rose Morrow, Ronya Strom, Elizabeth Ethier, Dylan Ritter, Alexander B.H. Henderson, Jalwa Afroz, Christopher A. Cassa, Nathan O. Stitziel, Rajat M. Gupta, Kelvin C. Luk, Lorenz Studer, Vikram Khurana, Shamil R. Sunyaev
NERINE tests gene network hypotheses with rare variant associations, identifying a subnetwork linked to Parkinson's disease.
Cell Genomics · Jun 22, 2026Peer-reviewedGenetics