Erinc Hallacli

Ancestral P-body proteins rewired for autophagic recyclingin the early land plant Marchantia polymorpha

This study identifies EDC4 and DCP1 as autophagy receptors for P-body turnover in Marchantia polymorpha, revealing lineage-specific adaptations and potential therapeutic applications.

Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of alpha-synuclein inclusions

This paper develops an iPSC platform to rapidly generate alpha-synuclein inclusions and investigates their formation, subtypes, and molecular interactions.

Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

The paper identifies a shared genetic risk module involving PSEN2 and actin regulation across alpha-synucleinopathies, linking them to Alzheimer's disease mechanisms.