Author

Autumn Rose Morrow

Brigham and Women's HospitalORCID 0000-0002-2301-9869Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Dylan RitteriD· 3 shared Lorenz StuderiD· 3 shared Ronya Strom· 3 shared Shamil R. SunyaeviD· 3 shared Sumaiya NazeeniD· 3 shared Vikram KhuranaiD· 3 shared Xinyuan WangiD· 3 shared Elizabeth Ethier· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Dylan RitterORCID

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4 papers

Recent·Most cited

NERINE reveals rare variant associations in gene networks across phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson's disease

Sumaiya Nazeen, Xinyuan Wang, Autumn Rose Morrow, Ronya Strom, Elizabeth Ethier, Dylan Ritter, Alexander B.H. Henderson, Jalwa Afroz, Christopher A. Cassa, Nathan O. Stitziel, Rajat M. Gupta, Kelvin C. Luk, Lorenz Studer, Vikram Khurana, Shamil R. Sunyaev

NERINE tests gene network hypotheses with rare variant associations, identifying a subnetwork linked to Parkinson's disease.

Cell Genomics · Jun 22, 2026Peer-reviewedGenetics

A single-cell genetic colocalization test improves power and resolves disease-mediating cell types

Jonathan Mitchel, Sumaiya Nazeen, Xinyuan Wang, Praveen K. Patnaik, Autumn Rose Morrow, Habib Nasir, Ronya Strom, Dylan Ritter, Lorenz Studer, Sung Chun, Chris J. Cotsapas, Vikram Khurana, Peter V. Kharchenko, Shamil R. Sunyaev

The paper introduces scJLIM, a cluster-free method for single-cell colocalization testing, improving power to link GWAS loci with gene expression changes in specific cell types.

bioRxiv · Oct 10, 2025 · PreprintGenomics

Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

Sumaiya Nazeen, Xinyuan Wang, Dina Zielinski, Isabel Lam, Erinc Hallacli, Ping Xu, Elizabeth Ethier, Ronya Strom, Camila A. Zanella, Vanitha Nithianandam, Dylan Ritter, Alexander Henderson, Nathalie G. Saurat, Jalwa Afroz, Andrew Nutter-Upham, , Vikram Khurana

The paper identifies a shared genetic risk module involving PSEN2 and actin regulation across alpha-synucleinopathies, linking them to Alzheimer's disease mechanisms.

bioRxiv · Mar 3, 2024 · PreprintGenomics

Neuropathology-based APOE genetic risk score better quantifies Alzheimer's risk

Yuetiva K. Deming, Eva Vasiljevic, Autumn Rose Morrow, Jiacheng Miao, Carol Van Hulle, Erin McMullen Jonaitis, Yue Ma, Vanessa M Whitenack, Gwendlyn Kollmorgen, Norbert Wild, Ivonne Suridjan, Leslie M. J. Shaw, Sanjay Asthana, Cynthia M. Carlsson, Sterling C. Johnson, , the Alzheimer's Disease Neuroimaging Initiative

The paper develops an APOE genetic risk score based on neuropathology that better explains CSF biomarker variance than traditional APOE ε4 metrics.

Alzheimer s & Dementia · Feb 16, 2023Peer-reviewedGenetic & Genomic Medicine