Author

James Duce

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexander J. WhitworthiD· 1 shared Clément Rey· 1 shared Emily Coode· 1 shared Gregory G. AldrediD· 1 shared John SkidmoreiD· 1 shared Jonathan H. ClarkeiD· 1 shared Maria Luisa GiudiciiD· 1 shared Maria ManifavaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexander J. WhitworthORCID

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1 paper

Recent·Most cited

Cross-platform multi-laboratory screening identifies HUWE1, USP33 and USP20 as negative-regulators of autophagy or mitophagy with relevance to neurodegeneration

Maria Luisa Giudici, Emily Coode, Wing Hei Au, Clément Rey, Maria Manifava, Ovidiu-Gabriel Capatina, Gregory G. Aldred, Stefan Milde, Verena Zyka, Wei‐Li Kuan, James Duce, Jonathan H. Clarke, Alexander J. Whitworth, Nicholas T. Ktistakis, John Skidmore

The paper identifies HUWE1, USP33, and USP20 as negative regulators of autophagy/mitophagy through cross-platform screening and validates their roles in neurodegeneration using multiple models.

bioRxiv · Sep 14, 2026 · PreprintNeuroscience