Author

James Hopkins

BC Cancer Agency

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:database / resource· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew J. J. MungalliD· 3 shared Richard A. MooreiD· 3 shared Eric Chuah· 2 shared Glenn ChangiD· 2 shared Jeremy Fan· 2 shared Kieran O’NeilliD· 2 shared Luka CulibrkiD· 2 shared Marco A. MarraiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Andrew J. J. MungallORCID

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Author profile →

3 papers

Recent·Most cited

Genomic structures and regulation patterns at HPV integration sites in cervical cancer

Vanessa Porter, Michelle Ng, Kieran O’Neill, Signe MacLennan, Richard Corbett, Luka Culibrk, Zeid Hamadeh, Marissa Iden, Rachel Schmidt, Shirng‐Wern Tsaih, Carolyn Nakisige, Martin Origa, Jackson Orem, Glenn Chang, Jeremy Fan, , Marco A. Marra

The paper uses long-read sequencing to analyze HPV integration sites in cervical cancer genomes, identifying structural and epigenetic impacts of integration.

Genome Research · Apr 1, 2025Peer-reviewedGenomics

Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes

Kieran O’Neill, Erin Pleasance, Jeremy Fan, Vahid Akbari, Glenn Chang, Katherine Dixon, Veronika Csizmók, Signe MacLennan, Vanessa Porter, Andrew Galbraith, Cameron J. Grisdale, Luka Culibrk, John H. Dupuis, Richard Corbett, James Hopkins, , Steven J.M. Jones

This paper presents a long-read sequencing dataset of cancer samples, showing its ability to resolve structural variants, haplotypes, and methylation patterns in precision medicine.

Cell Genomics · Oct 14, 2024Peer-reviewedGenetic & Genomic Medicine

Dissociation of solid tumour tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase associated stress responses

The CRUK IMAXT Grand Challenge Team, Ciara H. O’Flanagan, Kieran R. Campbell, Allen W. Zhang, Farhia Kabeer, Jamie L. Lim, Justina Biele, Peter D. Eirew, Daniel Lai, Andrew McPherson, Esther Kong, Cherie Bates, Kelly Borkowski, Matt Wiens, Brittany Hewitson, , Samuel A. J. R. Aparicio

This study identifies transcriptional stress responses in single-cell RNA-seq data from dissociated tumour tissues, showing that collagenase digestion induces a conserved stress response minimized by cold active protease.

Genome biology · Oct 17, 2019Peer-reviewedGenomics