Apical-Out Ileal Organoids: A Versatile Platform for Probing Gut-Nanomaterial Interactions
Dinh Son Vo, Alina Meyer, Foteini Tzioufa, Jens Eriksson, Ana C. C. Lopes, Maria Letizia Di Martino, Wojciech Fijalkowski, James Rae, Kajsa Björner, Johan Vessby, Robert G. Parton, Hanna M. G. Barriga, Mikael E. Sellin, Per Artursson, Madlen Hubert
This study establishes human apical-out ileal organoids as a model to study gut-nanomaterial interactions, showing charge-selective uptake regulated by the glycocalyx.
bioRxiv · Oct 13, 2026 · PreprintCell Biology