Author

Jan Kubicek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Felipe MerinoiD· 2 shared Achilleas S. FrangakisiD· 1 shared Ana B Gallego-Bellon· 1 shared Anja Seybert· 1 shared Anna Grimm· 1 shared Barbara Maertens· 1 shared Christoph Meisen· 1 shared Daniel Erkelenz· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Felipe MerinoORCID

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2 papers

Recent·Most cited

Membrane Proteins at Scale: Automated Copolymer Nanodisc Purification for Structure and Function

Philipp T. Hanisch, Lea Marie Esser, Felipe Merino, Nishika Sabharwal, Kaja A Reiffert, Sergej Balanda, Lukas Klemm, Ramona V. Busch, Michael Erkelenz, Ana B Gallego-Bellon, Daniel Erkelenz, Nina Heckmann, Christoph Meisen, Oliver Kortheuer, Roland Fabis, , Jan Kubicek

This paper introduces an automated copolymer screening platform for membrane protein solubilization, showing next-generation copolymers outperform classical ones across multiple human targets.

bioRxiv · Sep 5, 2025 · PreprintBiochemistry

Cryo-EM structure of a cell-free synthesized full-length human β1-adrenergic receptor in complex with Gs

Felipe Merino, Zoe Köck, Utz H. Ermel, Philipp Dahlhaus, Anna Grimm, Anja Seybert, Jan Kubicek, Achilleas S. Frangakis, Volker Dötsch, Daniel Hilger, Frank Bernhard

The paper determines the cryo-EM structure of a full-length human β1-adrenergic receptor in complex with Gs, revealing structural insights into ICL3's role in G protein activation.

Structure · Aug 25, 2025Peer-reviewedBiochemistry