Author

Jan-Hannes Schaefer

Scripps Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Jeffery W. KellyiD· 2 shared Akhil PrabhavalkariD· 1 shared Anthony BalistreriiD· 1 shared Christine BaaliD· 1 shared Claudia Cedeño KwongiD· 1 shared Evan T. PowersiD· 1 shared Gabriel C. LanderiD· 1 shared Jadon CompheriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Jeffery W. KellyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular and Structural Characterization Reveals Divergent Extracellular Vesicle Profiles Between Wild Type and Alzheimer's Disease Cerebrocortical Organoids

Anthony Balistreri, Natalie Turner, Jadon Compher, Mireya Almaraz, Akhil Prabhavalkar, Sachita Chittal, Sergio R. Labra, Kehinde Ezekiel, Christine Baal, Claudia Cedeño Kwong, Swagata Ghatak, Jan-Hannes Schaefer, Kimberly G. Vanderpool, Kathryn Spencer, John R. Yates, , Jeffery W. Kelly

The paper characterizes extracellular vesicles from Alzheimer's disease and wild-type cerebrocortical organoids, finding differences in size, membrane structure, and proteomic content.

bioRxiv · May 14, 2026 · PreprintNeuroscience

Helical Reconstruction of Amyloids in cryoSPARC

Jan-Hannes Schaefer, Robert T. O’Neill, Joseph P. Donnelly, Evan T. Powers, Jeffery W. Kelly, Gabriel C. Lander

This paper provides processing guidelines for helical reconstruction of amyloids using cryoSPARC, highlighting current capabilities and limitations while advocating for amyloid-specific parameter optimization.

Acta Crystallographica Section F Structural Biology Communications · May 5, 2026Peer-reviewedBioinformatics