Author

Mireya Almaraz

Scripps Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Jadon CompheriD· 3 shared Jeffery W. KellyiD· 3 shared Sergio R. LabraiD· 3 shared Stuart A. LiptoniD· 3 shared Akhil PrabhavalkariD· 2 shared Anthony BalistreriiD· 2 shared Christine BaaliD· 2 shared Claudia Cedeño KwongiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersNeuroscience

Jadon CompherORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Autophagy activator AA-20 engages CDK5 to promote lipophagy and improve neurodegeneration-associated phenotypes

Ee Phie Tan, Lydia Ambaye, Anne-Laure Mahul-Mellier, Yuting Zhang, Patricia Martinez-Botia, Sergio R. Labra, Lynee A. Massey, Zi Gao, Zainab Ahmed, Karina Nugroho, Carl Ash, Wen Ren, Christian M. Cole, Yin Wu, Sarah Ly, , Jeffery W. Kelly

AA-20 promotes lipophagy by activating lysosomal acid lipase and CDK5, reducing lipid droplet accumulation and improving neurodegeneration-associated phenotypes in cellular and organoid models.

bioRxiv · Nov 2, 2026 · PreprintMolecular Biology

Molecular and Structural Characterization Reveals Divergent Extracellular Vesicle Profiles Between Wild Type and Alzheimer's Disease Cerebrocortical Organoids

Anthony Balistreri, Natalie Turner, Jadon Compher, Mireya Almaraz, Akhil Prabhavalkar, Sachita Chittal, Sergio R. Labra, Kehinde Ezekiel, Christine Baal, Claudia Cedeño Kwong, Swagata Ghatak, Jan-Hannes Schaefer, Kimberly G. Vanderpool, Kathryn Spencer, John R. Yates, , Jeffery W. Kelly

The paper characterizes extracellular vesicles from Alzheimer's disease and wild-type cerebrocortical organoids, finding differences in size, membrane structure, and proteomic content.

bioRxiv · May 14, 2026 · PreprintNeuroscience

Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer's disease iPSC-derived cortical organoids

Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria V. Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, , Stuart A. Lipton

This study uses human iPSC-derived cortical organoids to model familial Alzheimer's disease and shows that autophagy activators reduce pathological Tau and Aβ accumulation and rescue synaptic loss.

Advanced Science · Jan 27, 2026Peer-reviewedNeuroscience