Author

Jason G. Cahoon

UConn Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Duomeng YangiD· 2 shared Tingting Geng· 2 shared Andrew G. HarrisoniD· 1 shared Anthony T. VellaiD· 1 shared Caroline Zielinski· 1 shared Chengliang WangiD· 1 shared Conner C. ChiariiD· 1 shared Evelyn TeraniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Duomeng YangORCID

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2 papers

Recent·Most cited

MEX3B is a positive pan-inflammasome regulator

Jason G. Cahoon, Tingting Geng, Duomeng Yang, Conner C. Chiari, Caroline Zielinski, Yanlin Wang, Penghua Wang

This study identifies MEX3B as a positive regulator of multiple inflammasomes, showing its role in caspase activation, pyroptosis, and cytokine secretion across different cell types.

bioRxiv · Apr 1, 2026 · PreprintImmunology

Unanchored ubiquitin chains promote the non-canonical inflammasome via UBXN1

Duomeng Yang, Jason G. Cahoon, Tingting Geng, Chengliang Wang, Andrew G. Harrison, Evelyn Teran, Yanlin Wang, Yanlin Wang, Anthony T. Vella, Vijay A. K. Rathinam, Jianbin Ruan

This study identifies UBXN1's role in activating the non-canonical inflammasome via unanchored ubiquitin chains, showing its importance in sepsis and inflammasome signaling.

bioRxiv · Oct 30, 2024 · PreprintImmunology