Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration
Jeremy W. Linsley, Kevan D. Shah, Nicholas A. Castello, Michelle Y. Chan, Dominik Haddad, Zak Doric, Shijie Wang, Wiktoria Leks, Jay Mancini, Viral D. Oza, Ashkan Javaherian, Ken Nakamura, David Kokel, Steven M. Finkbeiner
This paper introduces GEDI, a fluorescent biosensor that detects early irreversible commitment to cell death in neurons, enabling real-time and high-throughput analysis of neurodegeneration.
Nature Communications · Sep 6, 2021Peer-reviewedNeuroscience