Jean‐Luc Parent

This study investigates the K53N mutation in Gs isoforms, revealing isoform-specific loss- and gain-of-function effects contributing to disease mechanisms in endocrine and cardiac tissues.

This study shows that downregulating RAB4A reduces TNBC cell invasion and metastasis, and plasma from a TNBC patient during radiotherapy enhances invasiveness, which is blocked by RAB4A downregulation.