Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons
Marta Porniece, Jessica Baker, Charlotte D. Ausfahl, Stephen X. Zhang, Mark L. Andermann
This study shows that obesity alters the response dynamics of hypothalamic satiety neurons to food consumption, with high-fat diet-fed animals showing exaggerated early responses and reduced response progression during meals.
Scientific Reports · Oct 14, 2025Peer-reviewedNeuroscience