Stephen X. Zhang

This paper develops a micro-endoscope probe to simultaneously track multiple neuromodulators in real time using fluorescent sensors, demonstrating its use in brain slices and awake mice.

This study shows that obesity alters the response dynamics of hypothalamic satiety neurons to food consumption, with high-fat diet-fed animals showing exaggerated early responses and reduced response progression during meals.

The paper investigates how dopamine transmission and mating drive change over days in male mice, finding two mechanisms that regulate these slow-timescale dynamics.

The paper shows how stochastic neuropeptide signals (NPY and MSH) compete to regulate cAMP levels in neurons, influencing satiation through state-dependent integration.

The paper investigates dopamine-dependent cAMP dynamics in basal amygdala glutamatergic neurons during salient events, showing that cAMP responses decay more slowly than dopamine release and exhibit depression with repeated stimulation.

This study shows that juvenile hormone suppresses sexual motivation in young male Drosophila, and its decline allows the activation of latent courtship circuits.