Marta Porniece

This paper develops a micro-endoscope probe to simultaneously track multiple neuromodulators in real time using fluorescent sensors, demonstrating its use in brain slices and awake mice.

This study shows that obesity alters the response dynamics of hypothalamic satiety neurons to food consumption, with high-fat diet-fed animals showing exaggerated early responses and reduced response progression during meals.

The paper presents HYPOMAP, a comprehensive spatio-cellular map of the human hypothalamus, identifying BMI-associated genes and potential druggable targets.