Author
University of Illinois Urbana-Champaign
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Qi Wen Teo, Zongjun Mou, Wenkan Liu…·Nicholas C. Wu
This study quantifies the replication fitness effects of mutations in diverse H1N1 influenza neuraminidases, revealing strain-dependent effects and epistasis patterns.
Qi Wen Teo, Huibin Lv, Tossapol Pholcharee…·Nicholas C. Wu
This study shows TRIM21 acts as a molecular rheostat regulating influenza A virus replication by modulating ubiquitination and innate immune signaling, with PRKDC as a compensatory antiviral factor when TRIM21 is absent.
Huibin Lv, Walter N. Harrington, Wenkan Liu…·Nicholas C. Wu
This study characterizes antibody responses to H3 influenza A virus in mallard ducks, revealing unique features compared to human antibodies and highlighting gene conversion in antibody evolution.
Huibin Lv, Yang Wei Huan, Tossapol Pholcharee…·Nicholas C. Wu
This study identifies three IGHV3-23 antibodies targeting influenza HA stem, showing that non-neutralizing antibodies with enhanced Fc-mediated effector functions offer better in vivo protection than a potent neutralizer.
Huibin Lv, Yang Wei Huan, Qi Wen Teo…·Nicholas C. Wu
This study identifies an antibody that cross-reacts with H5N1 and H3N2 neuraminidases and shows how somatic hypermutation enables this cross-reactivity.