Intermittent AP-1 activation in muscles contributes to exercise-induced health benefits
Abhinav Choubey, S. Udhaya Kumar, Tingting Yang, Jennifer Jager, Sungguan Hong, Manashree Damle, Huiqi Yin, Ruxing Zhao, Chengchuang Song, Ege Sanem Oturmaz, H. N. Tong, Jason M. Puglise, Elisabeth R. Barton, Bin Fang, Zhaoyong Hu, , Zheng Sun
The paper shows that intermittent AP-1 activation in muscles mimics exercise benefits, improving mitochondrial function and glucose tolerance.
bioRxiv · Jan 6, 2026 · PreprintMolecular Biology