Ilse Rooman

This study identifies spatially distinct cell populations in human pancreatic ducts and shows that ASCP better preserves native cell identities compared to PDAC.

This study identifies ΔNP63 as a marker for exocrine-committed multipotent progenitors in the murine pancreas, showing its role in exocrine development and differentiation.

This study identifies 15 novel ductal cell populations in the mouse pancreas using scRNA-seq and investigates their roles in regeneration and exocrine pathogenesis.

This study shows that combining FOLFIRINOX with stereotactic body radiotherapy remodels pancreatic ductal adenocarcinoma, improving stromal and metabolic features and prognosis.

The paper predicts cancer cell-of-origin from DNA sequences by matching mutational landscapes to chromatin modification patterns in normal tissues.