Author

Isabelle Houbracken

Vrije Universiteit BrusselORCID 0000-0002-6676-9918Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ilse RoomaniD· 2 shared Jonathan BaldaniD· 2 shared Katarina CoolensiD· 2 shared Melissa Van der Vliet· 2 shared Meritxell RoviraiD· 2 shared Alejo Torres-CanoiD· 1 shared Catharina OlseniD· 1 shared Christelle BouchartiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Ilse RoomanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A Luminal-Basal Stratification of the Native Human Pancreatic Duct is Differentially Represented in Pancreatic Cancers

Jan-Lars Van den Bossche, Melissa Van der Vliet, Ellis Michiels, Oier Azurmendi Senar, Silke Van Lint, Zeynep Madran, Katarina Coolens, Jack Brons, Montserrat Nacher, Tatjana Arsenijevic, Nouredin Messaoudi, Pierre Lefesvre, Christelle Bouchart, Laurine Verset, Julie Navez, , Ilse Rooman

This study identifies spatially distinct cell populations in human pancreatic ducts and shows that ASCP better preserves native cell identities compared to PDAC.

Gut · Jun 4, 2026Peer-reviewedCancer Biology

ΔNP63 defines an exocrine-committed multipotent progenitor subset in the murine pancreas

Katarina Coolens, Melissa Van der Vliet, Jente Van Campenhout, Natalia del Pozo, Alejo Torres-Cano, Catharina Olsen, Jianming Xu, Rose-Anne Romano, Heiko Lickert, Meritxell Rovira, Isabelle Houbracken, Jonathan Baldan, Francisco X. Real, Francesca M. Spagnoli, Ilse Rooman

This study identifies ΔNP63 as a marker for exocrine-committed multipotent progenitors in the murine pancreas, showing its role in exocrine development and differentiation.

Cellular and Molecular Gastroenterology and Hepatology · Dec 25, 2025Peer-reviewedDevelopmental Biology