Jiao Yuan

Mechanism of fatty acid uptake and inhibition in human FATP2

This paper presents cryo-EM structures of human FATP2, revealing its fatty acid uptake mechanism and drug inhibition strategies.

SPCoral: diagonal integration of spatial multi-omics across diverse modalities and technologies

SPCoral integrates spatial multi-omics data across different modalities and technologies, improving spatial domain identification and cross-modal analysis.

SOAPy: a Python package to dissect spatial architecture, dynamics and communication

SOAPy is a Python package that analyzes spatial omics data to study spatial architecture, dynamics, and communication across various biological contexts.

Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment

This study identifies PRMT inhibitors as effective combinational therapies with PARP inhibitors to sensitize HR-proficient ovarian and breast cancer cells to treatment.

A Data-Intelligence-Intensive Bioinformatics Copilot System for Large-scale Omics Researches and Scientific Insights

This paper introduces a bioinformatics copilot system that combines AI and human expertise to enhance large-scale omics research and uncover biological insights.