Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy
Jacob E. Bridge, Matthew J. Johnson, Bibekananda Kar, Jihyun Kim, Sophia J. Wenthe, Joshua B. Krueger, Bryce J. Wick, Mitchell G. Kluesner, Andrew T. Crane, Jason Bell, Lage von Dissen, Erin M. Stelljes, Joseph G. Skeate, Branden S. Moriarity, Beau R. Webber
This paper develops a scalable, non-viral method to engineer and expand polyclonal γδ CAR-T cells, showing their functional efficacy and subset-specific responses in vivo.
Molecular Therapy · Mar 11, 2026Peer-reviewedImmunology