Pp6-Pfkfb1 axis modulates intracellular bacterial proliferation by orchestrating host-pathogen metabolic crosstalk
Li Fan, Yang Sun, Fangzhou Lou, Zilong Fang, Wen Ding, Xiangxiao Li, Yan Li, Qingqing Shen, Siyu Deng, Jihuan Liang, Fengjiao Zhang, Sibei Tang, Zhikai Wang, Xiaojie Cai, Jiajia Tong, , Honglin Wang
This study identifies the Pp6-Pfkfb1 axis as a key regulator of host-pathogen metabolic crosstalk that modulates intracellular bacterial proliferation in Salmonella-infected macrophages.
PLoS Pathogens · Dec 31, 2025Peer-reviewedMicrobiology