Author

Joel A Sexton

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron B. Schultz· 1 shared Alejandro V. VillarinoiD· 1 shared Amy E. KeatingiD· 1 shared Chengyu Liu· 1 shared Claudia HaferlachiD· 1 shared Foster BirnbaumiD· 1 shared Hye‐Kyung LeeiD· 1 shared Jichun CheniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Aaron B. Schultz

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1 paper

Recent·Most cited

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs

Hye‐Kyung Lee, Jichun Chen, Rachael Laura Philips, Sung‐Gwon Lee, Xingmin Feng, Zhijie Wu, Chengyu Liu, Aaron B. Schultz, Molly Dalzell, Manja Meggendorfer, Claudia Haferlach, Foster Birnbaum, Joel A Sexton, Amy E. Keating, John J. O’Shea, , Lothar G. Hennighausen

The paper investigates two STAT5B mutations in T cell leukemias, showing one causes gain-of-function and the other loss-of-function, with distinct impacts on immune cell populations and transcriptional activity.

Life Science Alliance · Apr 14, 2025Peer-reviewedGenetics