Author

Chengyu Liu

Guangxi Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genetics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aaron B. Schultz· 1 shared Alejandro V. VillarinoiD· 1 shared Amy E. KeatingiD· 1 shared Chenhao LiiD· 1 shared Claudia HaferlachiD· 1 shared Danping WeiiD· 1 shared Difeng Fang· 1 shared Dominic P. GoleciD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperGenetics

Aaron B. Schultz

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3 papers

Recent·Most cited

A tunable immune-evasion function of Zika virus NS5 governs viral fitness and pathogenesis

Yu Zhang, Yaqing Zhang, Chengyu LIU, Wenlin Ren, Chenhao Li, Yongqi Guo, Leyi Bai, Peigang Wang, Jing An, Jun Liu, Qiang Ding

This study identifies a single residue in ZIKV NS5 that modulates immune evasion, viral replication, and pathogenesis by affecting STAT2 degradation and IFN signaling.

bioRxiv · Jan 1, 2026 · PreprintMicrobiology

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs

Hye‐Kyung Lee, Jichun Chen, Rachael Laura Philips, Sung‐Gwon Lee, Xingmin Feng, Zhijie Wu, Chengyu Liu, Aaron B. Schultz, Molly Dalzell, Manja Meggendorfer, Claudia Haferlach, Foster Birnbaum, Joel A Sexton, Amy E. Keating, John J. O’Shea, , Lothar G. Hennighausen

The paper investigates two STAT5B mutations in T cell leukemias, showing one causes gain-of-function and the other loss-of-function, with distinct impacts on immune cell populations and transcriptional activity.

Life Science Alliance · Apr 14, 2025Peer-reviewedGenetics

Optimal CXCR5 Expression during Tfh Maturation Involves the Bhlhe40-Pou2af1 Axis

Xiaoliang Zhu, Xi Chen, Yaqiang Cao, Chengyu Liu, Zoey J. Kline, Gangqing Hu, Sundar Ganesan, Tibor Z. Veres, Difeng Fang, Shuai Liu, Danping Wei, Hirofumi Shibata, Dominic P. Golec, Hyunwoo Chung, Ronald N. Germain, , Jinfang Zhu

This study identifies the Bhlhe40-Pou2af1 axis as a transcriptional regulator of CXCR5 expression in Tfh cells, independent of the Bcl6-Blimp1 pathway.

bioRxiv · May 16, 2024Immunology