ImmunologyJournal of Clinical InvestigationPeer-reviewed
Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression
Joseph S. Dolina, Joey Lee, Spencer E. Brightman…·Stephen Philip Schoenberger
This study shows that combining CD4+/CD8+ T cell neoantigen vaccination with immune checkpoint blockade overcomes resistance and enables tumor regression in low TMB cancers.
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