Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathy
Michael Kohlhaas, Vasco Sequeira, Shan S. Parikh, Alexander Dietl, Olga Richter, Johannes Bay, Edoardo Bertero, Julia Schwemmlein, Xiao Yu Tian, Felix W. Friedrich, Frederik Flenner, Alexander G. Nickel, Felix Michael Alscher, Maithily S. Nanadikar, Raghav Venkataraman, , Christoph Maack
This study shows that mitochondrial reactive oxygen species contribute to arrhythmias in hypertrophic cardiomyopathy by disrupting calcium handling and electrical conduction.
bioRxiv · Oct 2, 2024 · PreprintPhysiology