Reconstitution of eukaryotic chromosomes and manipulation of DNA N6-methyladenine alters chromatin and gene expression
Leslie Y. Beh, Galia T. Debelouchina, Derek M. Clay, Robert E. Thompson, Kelsi A. Lindblad, Elizabeth R. Hutton, John R. Bracht, Robert P. Sebra, Tom W. Muir, Laura F. Landweber
This study identifies a novel DNA 6mA methyltransferase in ciliates and shows 6mA affects chromatin organization and gene expression.
bioRxiv · Nov 20, 2018 · PreprintBiochemistry