Author

Pola Kuhn

Tufts University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aimee SheniD· 2 shared Gang FangiD· 1 shared Gregory A. HarrisoniD· 1 shared John W. Ribis· 1 shared Larissa HaveyiD· 1 shared Mi NiiD· 1 shared Paula Caballero Blanco· 1 shared Shailab D. ShresthaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

Aimee ShenORCID

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Author profile →

2 papers

Recent·Most cited

Defining the order of assembly of the Clostridioides difficile divisome complex

Gregory A. Harrison, Pola Kuhn, Shailab D. Shrestha, Paula Caballero Blanco, Larissa Havey, Aimee Shen

This study defines the hierarchical order of divisome assembly in C. difficile using CRISPRi and fluorescent fusions, revealing a unique division mechanism distinct from model bacteria.

Journal of Bacteriology · Aug 27, 2026Peer-reviewedMicrobiology

A single DNA methylation site regulates cell fate during Clostridioides difficile sporulation.

Pola Kuhn, John W. Ribis, Mi Ni, Gang Fang, Aimee Shen

The paper identifies a single DNA methylation site that regulates sporulation in C. difficile by enhancing spoIIE transcription and sigmaF activation, revealing its role in pathogen persistence and potential as an antimicrobial target.

PLoS Pathogens · Jul 23, 2026Peer-reviewedMicrobiology