Minimally invasive delivery of peptides to the spinal cord for behavior modulation
Zhenghong Gao, Eric T. David, Tiffany W. Leong, Xiaoqing Li, Qi Cai, Juliet M. Mwirigi, Monica Giannotta, Elisabetta Dejana, John Wiggins, Sharada Krishnagiri, Robert M. Bachoo, Theodore John Price, Zhenpeng Qin
This paper presents a minimally invasive method to deliver peptides to the spinal cord for behavior modulation using optical stimulation of nanoparticles, demonstrating efficacy in inducing itching in mice without genetic modification.
bioRxiv · May 20, 2022 · PreprintNeuroscience