Author

John Zhang

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Abeer M. ShaabaniD· 1 shared Ahmed A. AhmediD· 1 shared Alastair Mark ThompsoniD· 1 shared Alejandro FILLON· 1 shared Alexandra W. van den Belt‐DuseboutiD· 1 shared Anargyros MegaliosiD· 1 shared Angelo FortunatoiD· 1 shared Anita E. GrigoriadisiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Abeer M. ShaabanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cognitive function depends upon Satb2 gene dosage in cortical projection neurons

Thomas S. Finn, Jeremiah Tsyporin, Min Dai, Sherry Jingjing Wu, Gabrielle Isabelle F. Servito, Xiaokuang Ma, John Zhang, Esther Park, Charlene Guo, Austin Shubert, Hailey Lizarraga, Ariella Angelini Stewart, Vipin Kumar, Giovanni J. Marrero, Yufei Si, , Bin Chen

This study shows that reduced Satb2 gene dosage in cortical projection neurons leads to chromatin and circuit defects, causing cognitive and sensory impairments in a mouse model of SATB2-associated syndrome.

bioRxiv · Jun 16, 2026 · PreprintNeuroscience

Genomic profiling defines variable clonal relatedness between invasive breast cancer and primary ductal carcinoma in situ

Esther H. Lips, Tapsi Kumar, Anargyros Megalios, Lindy L. Visser, Michael Sheinman, Angelo Fortunato, Vandna Shah, Marlous Hoogstraat, Emi Sei, Diego Mallo, Maria Roman-Escorza, Ahmed A. Ahmed, Mingchu Xu, Alexandra W. van den Belt‐Dusebout, Wim Brugman, , Elinor J. Sawyer

The paper uses genomic profiling to show that some invasive breast cancers are clonally unrelated to their preceding DCIS, suggesting DCIS may act as both a precursor and independent risk factor.

Nature Genetics · Jun 1, 2022Peer-reviewedGenetic & Genomic Medicine