Min Dai

The paper shows that somatosensory neuron repertoires in mammals diversify through changes to conserved neuron types, enabling adaptation to different habitats and body forms.

This study uses spatial transcriptomics and lineage tracing to show how tumor subclones drive microenvironmental changes that promote metastasis in a mouse model.

This study shows that reduced Satb2 gene dosage in cortical projection neurons leads to chromatin and circuit defects, causing cognitive and sensory impairments in a mouse model of SATB2-associated syndrome.

CellClick is an interactive platform that improves cell type annotation accuracy in single-cell and spatial omics data through automated and user-guided tools.

This study examines chandelier cell excitability in Dravet Syndrome mice, finding impaired excitability in juvenile and adult stages, distinct from basket cells.

LARIS identifies cell type-specific and spatially restricted ligand-receptor interactions in spatial transcriptomics data with high accuracy and scalability.

The paper shows that eGlyRs in hippocampal interneurons regulate network activity through developmental and evolutionary conserved mechanisms.

The paper identifies a novel inhibitory interneuron subtype in the dentate gyrus that selectively regulates mossy cell function and shows this pattern is evolutionarily conserved across species.

The paper identifies enhancer-AAV tools for specific neuronal subtypes and validates them across species.

DRED is a manually-curated database of 61 known and 516 predicted genes related to repeat expansion diseases, providing repeat information and links to external resources.

The paper shows pyramidal neurons influence the survival and identity of specific interneuron subtypes through non-synaptic mechanisms.

The paper shows that opioids suppress inhibition in hippocampal PV-INs but not neocortex across species and development, highlighting conserved and divergent roles in neural circuits.

COSG identifies marker genes for cell type distinction in single-cell and spatial transcriptome data with high accuracy and efficiency.