The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover
Chia Ching Wu, Isabel S. Naarmann‐de Vries, Jonas Hartmann, Zarina Nidoieva, Kevin Kopietz, Virginie Marchand, Zeynep Özrendeci, Doris Lindner, Sophia Schelchshorn, Sophia Flad, Michaela Frye, Fotini Nina Papavasiliou, Tanja Schirmeister, Georg Stoecklin, Johanna Schott, , Alessia Ruggieri
ViREn is a two-step method that purifies dengue virus RNA with high purity, revealing a 5-methylcytosine modification mediated by NSUN6 that affects RNA turnover.
Nucleic Acids Research · Jan 7, 2026Peer-reviewedBiochemistry