Author

Jonathan B. Allen

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amit ChoudharyiD· 1 shared Arghya DebiD· 1 shared Brian B. LiauiD· 1 shared Dhanushka N. P. Munkanatta Godage· 1 shared Ellen WeisbergiD· 1 shared Hui Si KwokiD· 1 shared James D. GriffiniD· 1 shared Jennifer A. RothiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Amit ChoudharyORCID

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1 paper

Recent·Most cited

Proximity-induced rewiring of oncogenic kinase triggers apoptosis

Manuel L. Merz, Veronika M. Shoba, Rajaiah Pergu, Zachary C. Severance, Dhanushka N. P. Munkanatta Godage, Arghya Deb, Hui Si Kwok, Prashant R. Singh, Sameek Singh, Jonathan B. Allen, Wenzhi Tian, Pallavi M. Gosavi, Santosh Kumar Chaudhary, Viktoriya S. Anokhina, Ellen Weisberg, , Amit Choudhary

This paper develops a small molecule, BRD8833, that induces BCR-ABL phosphorylation to disrupt its active site electric field, leading to loss of hyperactivity and apoptosis in BCR-ABL-dependent cancer cells.

ACS Central Science · Apr 9, 2026Peer-reviewedSynthetic Biology