YAP and TAZ couple osteoblast precursor mobilization to angiogenesis and mechanoregulated bone development
Joseph M. Collins, Annemarie Lang, Cristian Parisi, Yasaman Moharrer, Madhura P. Nijsure, Jong Hyun (Thomas) Kim, Gregory Lee Szeto, Ling Qin, Riccardo Gottardi, Nathaniel A. Dyment, Niamh C. Nowlan, Joel D. Boerckel
This study shows YAP and TAZ regulate osteoblast precursor mobilization and angiogenesis during bone development, linking mechanical cues to vascular and bone formation.
bioRxiv · Jan 20, 2023 · PreprintDevelopmental Biology