Yasaman Moharrer

This paper uses CRISPR-mediated conditional mutagenesis to show BMP/GDF signaling restricts postnatal bone overgrowth by regulating both periosteal and endosteal osteoblasts.

This study shows that erythroid precursors in the bone marrow increase local oxygen levels after injury, promoting tissue repair by enhancing angiogenesis and osteogenesis.

This study identifies YAP and TAZ as regulators of periosteal expansion during fracture repair, showing their role in cell proliferation and BMP4 regulation.

This study shows YAP and TAZ regulate osteoblast precursor mobilization and angiogenesis during bone development, linking mechanical cues to vascular and bone formation.

This study shows YAP and TAZ promote periosteal osteoblast precursor expansion and differentiation to accelerate bone fracture healing.